The Big Lead

2025 Heisman Trophy Odds entering Week 1 of college football season

Week 1 of the 2025 college football season is about to kick into full swing, and the Heisman Trophy betting odds paint an interesting picture entering the new year.

By Josh Sanchez

Texas Longhorns quarterback Arch Manning warms up before the game against the Mississippi State Bulldogs
Texas Longhorns quarterback Arch Manning warms up before the game against the Mississippi State Bulldogs / Daniel Dunn-Imagn Images
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The 2025 college football season is here and Week 1 is about to kick into full swing. This weekend, fans will be treated to some marquee matchups with two incredible top 10 showdowns that could have immediate Heisman Trophy indications.

On Saturday, the action kicks off at noon ET when the No. 1 Texas Longhorns travel to Columbus for a showdown with the No. 3 Ohio State Buckeyes. Texas is led by Heisman front-runner Arch Manning.

The other high-profile clash is a Battle of the Death Valleys with the No. 9 LSU Tigers taking on the No. 4 Clemson Tigers in primetime on ABC.

MORE: AP Top 25 College Football Rankings 2025: Preseason AP Poll

The game features the two quarterbacks sitting right behind Manning in the Heisman odds in Clemson's Cade Klubnik and LSU's Garrett Nussmeier.

Clemson Tigers quarterback Cade Klubnik runs for a game winning 50-yard touchdown against the Pittsburgh Panthers
Clemson Tigers quarterback Cade Klubnik runs for a game winning 50-yard touchdown against the Pittsburgh Panthers / Charles LeClaire-Imagn Images

Who else is in the Heisman Trophy picture as we prepare for a full dose of Week 1 action?

A full look at the latest Heisman Trophy betting odds entering the new season can be seen below, via FanDuel Sportsbook.

2025 Heisman Trophy betting odds

Detail view of the Heisman Trophy won by Southern California quarterback Caleb Williams
Detail view of the Heisman Trophy won by Southern California quarterback Caleb Williams / Brad Penner-Imagn Images
  • Arch Manning (Texas): +700
  • Cade Klubnik (Clemson): +900
  • Garrett Nussmeier (LSU): +900
  • Jeremiah Smith (Ohio State): +1200
  • Carson Beck (Miami): +1800
  • LaNorris Sellers (South Carolina): +1800
  • Drew Allar (Penn State): +1800
  • Ty Simpson (Alabama): +1800
  • Julian Sayin (Ohio State): +2000
  • Sam Leavitt (Arizona State): +2000
  • Dante Moore (Oregon): +2500
  • John Mateer (Oklahoma): +2500
  • Jackson Arnold (Auburn): +2500
  • DJ Lagway (Florida): +2500
  • Gunner Stockton (Georgia): +2500
  • Jeremiyah Love (Notre Dame): +3000
  • Marcel Reed (Texas A&M): +3500
  • Kevin Jennings (SMU): +3500
  • Austin Simmons (Ole Miss): +3500
  • CJ Carr (Notre Dame): +3500
  • Ryan Williams (Alabama): +4000
  • Miller Moss (Louisville): +5000
  • Fernando Mendoza (Indiana): +5000
  • Devon Dampier (Utah): +5000
  • Bryce Underwood (Michigan): +5000
  • Dylan Raiola (Nebraska): +6500
  • Demond Williams Jr. (Washington): +6500
  • Haynes King (Georgia Tech): +6500
  • Avery Johnson (Kansas State): +6500
  • Sawyer Robertson (Baylor): +6500

Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

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